2011
Natural product-inspired cascade synthesis yields modulators of centrosome integrityDuckert H, Pries V, Khedkar V, Menninger S, Bruss H, Bird A W, Maliga Z, Brockmeyer A, Janning P, Hyman A, Grimme S, Schurmann M, Preut H, Hubel K, Ziegler S, Kumar K, Waldmann H. Nat Chem Biol. 2011; 8 (2): 179-184. doi: 10.1038/nchembio.758
Recruitment of cyclin-dependent kinase 9 to nuclear compartments during cytomegalovirus late replication: importance of an interaction between viral pUL69 and cyclin T1Feichtinger S, Stamminger T, Muller R, Graf L, Klebl B, Eickhoff J, Marschall M. J Gen Virol. 2011; 92 (Pt 7): 1519-1531. doi: 10.1099/vir.0.030494-0
Structure-guided development of selective RabGGTase inhibitorsBon R S, Guo Z, Stigter E A, Wetzel S, Menninger S, Wolf A, Choidas A, Alexandrov K, Blankenfeldt W, Goody R S, Waldmann H. Angew Chem Int Ed Engl. 2011; 50 (21): 4957-4961. doi: 10.1002/anie.201101210
Total synthesis and biological evaluation of (-)-englerin A and B: synthesis of analogues with improved activity profileRadtke L, Willot M, Sun H, Ziegler S, Sauerland S, Strohmann C, Frohlich R, Habenberger P, Waldmann H, Christmann M. Angew Chem Int Ed Engl. 2011; 50 (17): 3998-4002. doi: 10.1002/anie.201007790
Discovery of (7R)-14-cyclohexyl-7-{[2-(dimethylamino)ethyl](methyl) amino}-7,8-dihydro-6Hindolo[1,2-e][1,5]benzoxazocine-11-carboxylic acid (MK-3281), a potent and orally bioavailable finger-loop inhibitor of the hepatitis C virus NS5B polymeraseNarjes F, Crescenzi B, Ferrara M, Habermann J, Colarusso S, Ferreira Mdel R, Stansfield I, Mackay A C, Conte I, Ercolani C, Zaramella S, Palumbi M C, Meuleman P, Leroux-Roels G, Giuliano C, Fiore F, Di Marco S, Baiocco P, Koch U, Migliaccio G, Altamura S, Laufer R, De Francesco R, Rowley M. J Med Chem. 2011; 54 (1): 289-301. doi: 10.1021/jm1013105
Protein Kinases as Drug Targets: 49 (Methods and Principles in Medicinal Chemistry)Klebl B, Müller G, Hamacher M, Mannhold R, Kubinyi H, Folkers G. 2011. 1 ed. Wiley-VCH Verlag GmbH & Co. KGaA.
